REINWERK Cleanroom & Plant Engineering | ISO 14644 & GMP Compliance
Turnkey Modular Cleanrooms & Controlled Environments
DE | EN
ISO Class 1 to ISO Class 9 • GMP Grade A, B, C, D

Precision Cleanroom HVAC & Microclimate Engineering

Engineered laminar and turbulent airflow systems delivering micro-filtered air, continuous pressure differentials, and precise temperature & humidity regulation.

Technical Overview

Engineered Contamination Control

Contamination control begins with flawless aerodynamic engineering. REINWERK designs and integrates turnkey cleanroom HVAC systems that ensure unyielding particle removal, continuous positive/negative differential pressure, and stringent microclimate stability.

Our systems utilize state-of-the-art electronically commutated (EC) fan technology, demand-controlled ventilation (DCV), and high-efficiency heat recovery wheels—reducing energy consumption by up to 35% while maintaining regulatory compliance 24/7.

Key Engineering Features

Multi-Stage HEPA & ULPA Filtration

Pre-filtration (ISO Coarse / ePM1) coupled with terminal H14 HEPA (99.995% @ 0.3 µm) and U15-U17 ULPA filters for ultra-critical particle trapping.

Differential Pressure Cascades

Automated active pressure regulation maintaining 10 Pa to 25 Pa pressure differentials between adjacent classification zones to prevent cross-contamination.

Stringent Climate Regulation

Precision temperature control down to ±0.2°C and relative humidity regulation down to ±2% RH for sensitive electronic, chemical, and biologics processes.

Real-time BMS Integration

Continuous monitoring of airflow velocities, filter differential pressure (dP), room temperatures, and humidity with automated audit logging.

Deployment & Delivery Lifecycle

01
Thermodynamic & CFD Modeling
Calculating heat loads, air change volumes, and simulating particle dispersion vectors in computational fluid dynamics.
02
AHU & Ductwork Specification
Selecting hygiene-certified air handling units with double-skinned insulated casing and zero-leakage dampers.
03
Ductwork Erection & Leak Testing
Installing airtight stainless or galvanized ductwork sealed to Eurovent Class C/D standards.
04
Air Balancing & Smoke Studies
Balancing air velocities and performing visual airflow smoke testing to verify laminar flow uniformity.

Technical Specifications

Terminal Filtration EN 1822 certified H14 HEPA (99.995%) or U15-U17 ULPA (99.99995%)
Air Change Rates From 15 to over 300 Air Changes per Hour (ACH) depending on ISO class
Temperature Stability Standard: 20°C ± 1°C; Precision option: ± 0.2°C
Humidity Stability Standard: 45% ± 5% RH; Low-dewpoint options to < 1% RH
Fan Technology Direct-drive backward curved EC centrifugal blowers (IE5 efficiency)
Acoustic Levels < 55 dB(A) in operating room zones via integrated silencers

Typical Applications:

Aseptic Filling & Bio-Processing Wafer Fabrication & Nanotechnology API Synthesis & Hazardous Chemical Handling Optics & Satellite Component Testing Sterile Injectables Production
Engineering FAQs

Frequently Asked Questions

What is the difference between laminar airflow and turbulent airflow?

Laminar (unidirectional) airflow moves filtered air in parallel streams at uniform velocity (typically 0.36 to 0.45 m/s), sweeping particles directly away from critical zones (e.g. ISO 5 / GMP Grade A). Turbulent (non-unidirectional) airflow mixes conditioned air to dilute particulate concentration (typical in ISO 6 to 8).

How does REINWERK optimize cleanroom energy consumption?

Cleanroom HVAC is energy-intensive. We integrate variable-speed EC fans, automated night setback modes, high-efficiency enthalpy heat recovery, and intelligent damper modulation that adjust air volume in real time based on occupancy.

Plan Your Controlled Environment

Ready to Build or Upgrade Your Cleanroom Facility?

Whether you require a turnkey GMP Grade A sterile suite, an ISO Class 4 microelectronics cleanroom, or regulatory re-certification, REINWERK delivers German engineering excellence from concept to handover.